NCLEX Pharm Focus
Does Pharmacology cause you much anxiety? According to the National Council State Board of Nursing (NCSBN), Pharmacological and Parental Therapy represent 12-18% of the RN NCLEX exam while 11-17% represent a portion of the PN NCLEX exam. With this in mind, familiarizing yourself with the commonly asked medications is an important part of your NCLEX preparation.

Benazepril hydrochloride

Brand Name(s):

  • Lotensin

Pharmacologic Class:

  • Angiotensin-converting enzyme (ACE) inhibitor
  • Hypertension


  • Inhibits ACE, preventing conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. Less angiotensin II decreases peripheral arterial resistance, decreasing aldosterone secretion, which reduces sodium and water retention and lowers blood pressure.
Adverse Reactions:
  • CNS: headache, dizziness, drowsiness, fatigue, somnolence
  • CV: symptomatic hypotension
  • GU: impotence
  • Metabolic: hyperkalemia
  • Musculoskeletal: arthralgia, arthritis, myalgia
  • Respiratory: dry, persistent, nonproductive cough
  • Other: hypersensitivity reactions, angioedema
Nursing Considerations:
  • Measure blood pressure when drug level is at peak (2 to 6 hours after administration) and at trough (just before a dose) to verify adequate blood pressure control.
  • Don’t confuse benazepril with Benadryl or Lotensin with Loniten or lovastatin.

Patient Teaching:

  • Instruct patient to avoid salt substitutes containing potassium. May cause hyperkalemia.
  • Inform patient that light-headedness can occur. Tell him to rise slowly to minimize this effect.
  • Warn patient to use caution in hot weather and during exercise. Inadequate fluid intake, vomiting, diarrhea, and excessive perspiration can lead to light-headedness and fainting.
  • Advise patient to report signs of infection, such as fever and sore throat. Tell him to call prescriber if he develops easy bruising or bleeding; swelling of tongue, lips, face, eyes, mucous membranes, or extremities; difficulty swallowing or breathing; or hoarseness.
Phone: 1-650-303-5488
Office: 90 So. Spruce Ave. Suite P
South San Francisco, CA 94080

D&D Nursing Educators, Inc., 90 So. Spruce Ave. Suite P South San Francisco, CA 94080

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